Input & opinions from the experts     Transfer Factor Plus Advanced™ Offers Unprecedented Immune Boosting Ability  Tests from The Institute of Longevity Medicine - Darryl See, M.D.

Immune System Basics

Components of the Immune System: Organs and Cells Many organs throughout your body have an essential role in the development and structure of the immune system, including your bone marrow, thymus, lymph nodes, spleen, tonsils and adenoids and appendix. These organs are responsible for the growth, development and deployment of lymphocytes, the white cells that are the key laborers of the immune system. The primary lymphocytes are B-cells, T-cells, natural killer cells, macrophages and dendritic cells. Each has a specific role in keeping your body and immune system healthy. The Immune Response Primary Immune Response The first time your body is exposed to particular viruses or bacteria, it takes time for your immune system to recognize the invading organisms and to figure out how to kill them. During this elapsed time, bacteria and viruses grow exponentially, thus increasing the amount of time it takes to completely eliminate the infection. A cut in the skin damages cells and allows bacteria into the body signaling an immune response from macrophages and other scavenger immune cells. Mast cells release chemicals that trigger inflammation, allow-ing other immune cells to rush to the problem area. Before reinforcements arrive, macrophages and other prestationed immune cells start attacking bacteria, chop them up into bits called antigens. They are then transported to lymph nodes where these macrophages attach to B cells and T cells. B cells begin producing antibodies specifically for the particular antigens or germs the body is exposed to. The antibodies trigger responses from certain immune cells like NK cells, macrophages and killer T cells to engulf and kill the bacteria-infected cells. Helper T cells signal the antibodies and killer T cells to go directly to the wound. While the immune cells are taking care of the germs, other cells called platelets begin healing the wound by forming clots which close the wound. Secondary Immune Response The second time the body is exposed to a particular virus or bacteria, the immune system recognizes the invading organism more quickly and immediately knows how to fight it off. Because the amount of time in these steps is shorter, the infection can be eliminated more quickly. Transfer Factor triggers a secondary immune response by borrowing the immune memory of the cow or the chicken. A cut in the skin damages cells and allows bacteria into the body signaling an immune response from macrophages and other scavenger immune cells. Mast cells release chemicals that trigger inflammation, allowing other immune cells to rush to the problem area. Before reinforcements arrive, macrophages and other pre-stationed immune cells start attacking bacteria, chop them up into bits called antigens. B cells, set in motion by previous immune responses, begin producing antibodies specifically for the particular antigens or germs the body is exposed to. The antibodies trigger responses from certain immune cells like NK cells, macrophages and killer T cells to engulf and kill the bacteria-infected cells. Helper T cells signal the antibodies and killer T cells to go directly to the wound. While the immune cells are taking care of the germs, other cells called platelets begin healing the wound by forming clots which close the wound.

Immune System and Other Body Systems

The immune system is closely connected to virtually every other system of the body. When it isn’t functioning at its best, the rest of your body suffers and you’re left vulnerable to a host of foreign invaders. And like every other part of your body, the immune system needs nutrients to function optimally. If you treat your body badly with junk food, little or no exercise and a stressful lifestyle, your immune system has to work overtime to protect you. The Role of Inflammation Inflammation is an immediate response by the immune system to an infection or injury, such as when you get a cut on your arm. In most cases, as the immune system deals with the problem, the immune cells then retreat from the area and inflammation and swelling go down. But occasionally, the immune cells do not withdraw and the inflammation continues, creating a chronic problem within the body. Chronic inflammation has gained recent attention with the medical and scientific communities because of its role in driving many of the most feared illnesses of middle and old age. Scientific research supports that managing the inflammatory response and supporting the immune system in the first place is the best approach for life-long health.

Duane Townsend, M.D. OB/GYN & Oncologist, has had more than 32 years of distinguished experience in the medical field.  He pioneered a surgical technique for the treatment of pre-malignant disease of the uterine cervix.  In addition, he has authored more than 90 scientific papers in peer review journals as well as over 15 chapters in research books. "I'm a cancer physician. I primarily treat female cancer and certainly encourage my patients who are undergoing chemotherapy and radiation therapy to take Transfer Factor™.  It helps to modulate the immune system.  I have patients with chronic herpes infections who are taking Transfer Factor™ on a regular basis and it's reducing the number of outbreaks.  I've also had patients with chronic yeast infections, and the Transfer Factor™ has reduced their infections as well.  Transfer Factor™ is a science-based product with excellent data from a variety of researchers." David Markowitz, M.D.  "I believe Transfer Factor™ is, without a doubt, the greatest discovery of the century.  Modulating the immune system will be the primary way to stay well in the future.  This nutrient can affect the immune system like nothing else can. Everyone needs to consume this product." Kenneth Singleton, M.D., M.P.H.  "4Life Transfer Factor™ is the most exciting product for the immune system that I've seen in my eighteen years of practicing medicine.  It has literally revolutionized my practice, particularly in terms of chronic diseases." Kenneth Bock, M.D.  "Immune imbalance underlies many chronic illnesses. Because Transfer Factor™ can function as an immune modulator, it can help to restore immune system balance in many types of clinical situations."  Rob Robertson, M.D.  "With Transfer Factor™ we can teach our immune systems how to deal with millions of microorganisms. This is big news in preventive medicine." "As I learned what the company was going to become, I sold my medical practice and my nutritional supplement company.  I became a 4Life™ distributor in January 1998.  It was one of the best decisions, if not the best decision, I have ever made." June Ferrari, N.D., C.N.C. "Transfer Factor™ is the gift from nature that supplies the essential tools for the regulation of our immune systems, in order to properly address the challenges we face in today's toxic world.  Transfer Factor™ provides the body with an arsenal of defense, unleashing the true power of the immune system."  Dr. William Hennen: "Transfer factors are the most exciting discovery in immunology. As the 21st Century unfolds, transfer factor will be one of our greatest keys to health and well being."  Cynthia Olson, ND, CNC  "The success that we have experienced with Transfer Factor Plus™ has been nothing short of astonishing.  Transfer Factor Plus™ is creating a paradigm shift in how we perceive and treat disease." Dr. Joe Ramaekers, DVM  "Transfer Factor™ is truly the missing link in the nutritional approach to preventive medicine for all pets.  It is a powerful immune system activator that has the ability to boost the immune system in an entirely different way.  The new TF Pets™ products for dogs and cats are phenomenal.  My patients love them." Michael Traub, N.D.   "The period once euphemistically called the Age of the Miracle Drug is now dead. And the indiscriminate use of antibiotics is leading us to one of the most frightening eras in recent memory. That is, the return of infectious diseases for which there is no effective treatment. Two decades following the introduction of antibiotics, the medical community began to see a disturbing trend. Bacterial infections that were once treatable no longer responded to antibiotics. Penicillin is effective today against only 10 percent of the strains of Staphylococcus aureus that it used to eradicate easily. Those that did respond often required five to ten times the dose of the drug that previously was effective."  Key Formulations in Transfer Factor Plus™ Transfer Factor XF™ This is 4Life™ ’s original proprietary extract of transfer factors. Derived from bovine colostrum, transfer factors are immune system molecules that contain the intelligence codes for immune recognition and balance.*  They literally transfer immunity across species from a competent host to a recipient.* ThyRx™  is 4Life™ ’s proprietary thymus complex which contains thymic factors. ThyRex™ contains a patented thymic protein as well as other important proprietary thymic factors which support T-cells.*  Uneducated lymphocytes receive their training from thymus factors to become mature T-Suppressor and T-Helper Cells and Cytotoxic T-Lymphocytes. Cordyvant™  Cordyvant™ is a proprietary combination of glyconutrients ( IP6, Cordyceps, Maitake and Shiitake mushrooms, Beta Glucans and Aloe) which support the innate immune system.*  In addition, glyconutrients activate white blood cells to produce antibodies without the help of T-cells.

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Transfer Factor™ Testing -  Transfer Factor Study with 20 Cancer Patients  Jeunesse Inc.  Institute of Longevity Medicine Darryl See, M.D.  Director, Bioassay Laboratory Preliminary Report (additional test results to follow) Transfer Factor™ Testing Background and rationale: 1) Cancer is the second leading cause of death in the US. The rate of nearly every type of cancer is on the rise. Despite billions of dollars in research, the mortality rate has remained nearly unchanged since the 1960's using conventional treatments such as radiation, surgery and chemotherapy. Thus, there is considerable interest in using immune modulation as an adjuvant for cancer therapy. Natural killer cells are particularly important in destroying cancer cells. Purpose of study: 1) To determine the in vitro anti-cancer effects of Transfer Factor™ and Transfer Factor Plus™ using PBMC isolated from human volunteers and assaying the increased ability of the NK cell population to kill K562 erythroleukemic cells. Methods: 1) PBMC killing of K562 (erythroleukemic) cells    Results: 1) Transfer Factor™ increased NK-cell killing by 103%             Transfer Factor Advanced™ increased NK-cell killing by 248% Conclusions: Transfer Factor™ and Transfer Factor Plus™ induced immune-based lysis of K562 cells at a level unprecedented in the director's experience or in the known medical literature. Since NK cell function is so crucial in killing cancer cells, these products are ideal candidates for cancer adjuvant therapy. In addition, NK cells form a first line of defense against infections from viruses and certain other microorganisms. Killing assays against K562 cells have also been correlated with increased activity against chronic and acute infections as well. Darryl See, M.D.  Director, Bioassay Laboratory Institute of Longevity Medicine     Nutraceutical induced increase in Natural Killer cell activity Nutriceutical % Rise in Natural Killer cell activity   Transfer Factor Advanced™ 248 %   Transfer Factor™ 103 %   IP6  (highest of group previously tested) 49 %   Plant Polysaccharide Formula 48 %   Echinacea 43 %   Shiitake Mushroom 42 %   Cordeceps Formula 28 %   Bovine Colostrum 23 %   Phytonutrient Formula 21 %   Endocrine System Formula 16 %   Aloe Vera Concentrate (acemannan) 15 %   Noni  (Morinda Citrafolia) 15 % Note: Over the years, Jeunesse Inc. has tested 196 nutraceuticals. 152 of these products increased effectiveness from 0 to 10%.  Only 44 products did better than 10%.  40% of these products were too toxic to use without caution. Until now, IP6 showed the highest increase at 49%.  Transfer Factor™ has been shown to be the most powerful product on the market, with a toxicity level of ZERO. Transfer Factor Study with 20 Cancer Patients  Darryl See, M.D. conducted the following studies.  Twenty patients, 12 men and 8 women, were selected for this in vivo study.  The average age was 49.3.  The twenty individuals were each level 3 or level 4 cancer patients.  Each patient was basically sent home by his or her oncologist to die.  The average life expectancy was 3.7 months.   The protocol was to place each patient on 9 capsules per day of Transfer Factor Plus™.  The patients were given a number of other general nutrients*.  After eight months, 16 of these individuals were still living and were either in remission, improving or stabilized. The baseline for natural killer cell function was 6.4.  Within 4 weeks the average NK Cell function was increased to 25.7 and in 6 months it increased to 27.6.  This represented a 400% increase in NK Cell function.  This is an ongoing study.  This study has been submitted to a peer reviewed publication.  *Antioxidants, Digestive Enzymes, Probiotics and multi-vitamins.  The following study was conducted at the Institute of Longevity.  The purpose of the study was to examine the synergistic effects of the components of Transfer Factor Plus™.  Each component was tested separately and then tested as a whole unit.  Together the proprietary blend increased NK Cell functions more than the sum total of all of the ingredients tested separately.  This study indicates that the intelligence contained in Transfer Factor™ has an enhancing effect on other nutrients. In vitro study: Ingredient 10 GM /ml NK Function PBMC (Control) 25.6%  Zinc 26.8% NS  Proprietary Blend 59.9% <0.02 (Mushrooms etc)  Zinc +Prop. Blend 95.4 <0.01  Transfer Factor™ alone 128.5% <0.01  Complete Prod. (Transfer Factor Plus™) 273.6% <0.01  The sum of the individual product is less than the Complete Product (Transfer Factor Plus™). There is synergy in having a combination of Transfer Factor Plus™.     The  information has not been evaluated by the FDA or by 4Life™ Research.  We do not claim that 4Life™ products directly prevent, or cure any disease.  We do not suggest that anyone should replace traditional medical treatment with our products.  4Life™ products are promoted for their ability to enhance the effectiveness of our natural immune system functions.  On this web site you will be exposed to many testimonies and nutritional ideas. We encourage you to use common sense and prudence in evaluating testimonies.  Testimonies can be based on "placebo effects," which basically means that you can experience temporary results just because you really believe you will.  Research can be complicated to translate into real life situations.  Even medical doctors may disagree on certain subjects.  It is our desire to expose you to many different ideas for your consideration.  Our focus is on supporting the immune system, which can assist your body in the healing process.  The testimonies and information on this web site only represent the opinions of the individuals involved.  We encourage you to use common sense in your expectations in consuming any nutritional product. All material provided in this site is provided for educational purposes only. The information provided may not be relied upon for diagnosis or treatment of any disease or medical condition. Seek advice from your health care professional regarding the applicability of any information, opinion or recommendation for diagnosis or treatment of any symptoms or medical condition. Statements about products and health conditions have not been evaluated by the U.S. Food & Drug Administration. Products of 4Life Research are not intended to diagnose, treat, cure, or prevent any disease.